CO2-induced ocean acidification increases anxiety in rockfish via alteration of GABAA receptor functioning
| dc.contributor.author | Hamilton, Trevor | |
| dc.contributor.author | Holcombe, Adam | |
| dc.contributor.author | Tresguerres, Martin | |
| dc.date.accessioned | 2022-05-27T01:14:59Z | |
| dc.date.available | 2022-05-27T01:14:59Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | The average surface pH of the ocean is dropping at a rapid rate due to the dissolution of anthropogenic CO2, raising concerns for marine life. Additionally, some coastal areas periodically experience upwelling of CO2-enriched water with reduced pH. Previous research has demonstrated ocean acidification (OA)-induced changes in behavioural and sensory systems including olfaction, which is due to altered function of neural gamma-aminobutyric acid type A (GABAA) receptors. Here, we used a camera-based tracking software system to examine whether OA-dependent changes in GABAA receptors affect anxiety in juvenile Californian rockfish (Sebastes diploproa). Anxiety was estimated using behavioural tests that measure light/dark preference (scototaxis) and proximity to an object. After one week in OA conditions projected for the next century in the California shore (1125 ± 100 µatm, pH 7.75), anxiety was significantly increased relative to controls (483 ± 40 µatm CO2, pH 8.1). The GABAA-receptor agonist muscimol, but not the antagonist gabazine, caused a significant increase in anxiety consistent with altered Cl− flux in OA-exposed fish. OA-exposed fish remained more anxious even after 7 days back in control seawater; however, they resumed their normal behaviour by day 12. These results show that OA could severely alter rockfish behaviour; however, this effect is reversible. | |
| dc.description.uri | https://library.macewan.ca/cgi-bin/SFX/url.pl/87B | |
| dc.identifier.citation | Hamilton, T. J., Holcombe, A., & Tresguerres, M. (2014). CO2-induced ocean acidification increases anxiety in rockfish via alteration of GABAA receptor functioning. Proceedings. Biological sciences, 281(1775), 20132509. https://doi.org/10.1098/rspb.2013.2509 | |
| dc.identifier.doi | https://doi.org/10.1098/rspb.2013.2509 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14078/495 | |
| dc.language | English | |
| dc.language.iso | en | |
| dc.rights | All Rights Reserved | |
| dc.subject | gabazine | |
| dc.subject | muscimol | |
| dc.subject | Sebastes | |
| dc.subject | upwelling | |
| dc.title | CO2-induced ocean acidification increases anxiety in rockfish via alteration of GABAA receptor functioning | en |
| dc.type | Article | |
| dspace.entity.type |