Sodium methyl carbonate as an effective C1 synthon. Synthesis of carboxylic acids, benzophenones, and unsymmetrical ketones

Author
Hurst, Timothy E.
Deichert, Julie A.
Kapeniak, Lucas
Lee, Roland
Harris, Jesse
Jessop, Philip G.
Snieckus, Victor
Faculty Advisor
Date
2019
Keywords
sodium methyl carbonate , synthesis of symmetrical ketones , unsymmetrical ketones , Grignard reagents , organolithium , C1 synthon , alkyl metal carbonates , carboxylic acids , benzophenones
Abstract (summary)
Reported is the synthesis of carboxylic acids, symmetrical ketones, and unsymmetrical ketones with selectivity achieved by exploiting the differential reactivity of sodium methyl carbonate with Grignard and organolithium reagents.
Publication Information
Timothy E. Hurst, Julie A. Deichert, Lucas Kapeniak, Roland Lee, Jesse Harris, Philip G. Jessop and Victor Snieckus. Sodium Methyl Carbonate as an Effective C1 Synthon. Synthesis of Carboxylic Acids, Benzophenones, and Unsymmetrical Ketones, Organic letters, (2019) 21, 11, 3882-3885
DOI
Notes
Item Type
Article
Language
English
Rights
All Rights Reserved