Use of a switchable-hydrophilicity solvent as both a solvent and a catalyst in aldol condensation

Author
Poole, Hailey
Gauthier, Jeremy
Vanderveen, Jesse R.
Jessop, Philip G.
Lee, Roland
Faculty Advisor
Date
2019
Keywords
switchable-hydrophilicity solvent , N,N-dimethylcyclohexylamine , aldol condensation , waste treatment , recyclable catalyst
Abstract (summary)
A switchable-hydrophilicity solvent, N,N-dimethylcyclohexylamine, was used as a recyclable catalyst and solvent for aldol condensation, giving >97% pure product in 94% isolated yield without the need for purification or additional solvents. CO2-triggered separation produced yields greater than conventional workup and allowed facile recycling of the amine.
Publication Information
Hailey Poole, Jeremy Gauthier, Jesse Vanderveen, Philip G. Jessop and Roland Lee. 2019. Use of a switchable-hydrophilicity solvent as both solvent and catalyst in aldol condensation. Green chemistry, 21 (23), pp. p6263-p6267 DOI: 10.1039/c9gc02593f
DOI
Notes
Item Type
Article
Language
English
Rights
All Rights Reserved