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Asymmetric synthesis of (1R,2S,3R)-gamma-methyl-cis-pentacin by a kinetic resolution protocol

Faculty Advisor

Date

2002

Keywords

asymmetric synthesis, kinetic resolution protocol

Abstract (summary)

The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-amino-cyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-alpha-methylbenzylamide.

Publication Information

Bailey, S., Davies, S. G., Smith, A. D., & Withey, J. M. (2002). Asymmetric synthesis of (1R,2S,3R)-gamma-methyl-cis-pentacin by a kinetic resolution protocol. Chemical Communications, (23), 2910-2911. DOI: 10.1039/b209728c

Notes

Item Type

Article

Language

English

Rights

All Rights Reserved