On the classical vibrational coherence of carbonyl groups in the selectivity filter backbone of the KcsA ion channel

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Title: On the classical vibrational coherence of carbonyl groups in the selectivity filter backbone of the KcsA ion channel
Author(s) or Creator(s): Salari, Vahid
Sajadi, Maryam
Bassereh, Hassan
Rezania, Vahid
Alaei, Mojtaba
Tuszynski, Jack
Date: 2015
Peer Reviewed?: Yes
Keywords: KcsA ion channel
selectivity filter
carbonyl groups
vibrational frequency
degree of coherence
Pearson correlation
Description: It has been suggested that quantum coherence in the selectivity filter of ion channel may play a key role in fast conduction and selectivity of ions. However, it has not been clearly elucidated yet why classical coherence is not sufficient for this purpose. In this paper, we investigate the classical vibrational coherence between carbonyl groups oscillations in the selectivity filter of KcsA ion channels based on the data obtained from molecular dynamics simulations. Our results show that classical coherence plays no effective role in fast ionic conduction.
Publication Information: Salari, V., Sajadi, M., Bassereh, H., Rezania, V., Alaei, M., & Tuszynski, J. A. (2015). On the classical vibrational coherence of carbonyl groups in the selectivity filter backbone of the KcsA ion channel. Journal of Integrative Neuroscience, 14(2), 195-206. doi:10.1142/S0219635215500132
Type of Item: Journal Articles
Language: English
Location: https://roam.macewan.ca/islandora/object/gm:706

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