Azide trapping of metallocarbenes: generation of reactive C-acylimines and domino trapping with nucleophiles

Bott, TinaAtienza, Bren JordanWest, F. G.2021-05-172022-05-312022-05-312014Bott, T. M., Atienza, B. J., West, F. G. Azide. (2014). Azide trapping of metallocarbenes: generation of reactive C-acylimines and domino trapping with nucleophiles.RSC Advances, 4(60), 31955-31959. https://doi.org/10.1039/C4RA06044Jhttps://hdl.handle.net/20.500.14078/2277Azide-tethered diazocarbonyl compounds undergo copper-catalyzed conversion to transient C-acylimines. These reactive intermediates can be trapped with a variety of carbon nucleophiles, giving rise to complex 3-indolinone frameworks, including those with adjacent tetra-substituted carbon centers, in a single transformation.514.16KBPDFenAll Rights Reservedazide-tethered diazocarbonylC-acyliminesnitrogen heterocyclestertiary aminecarbonyl ylidesSchmidt rearrangementaziridination of electron-deficient alkenesdinitrogenbetainenucleophileAzide trapping of metallocarbenes: generation of reactive C-acylimines and domino trapping with nucleophilesArticlehttps://doi.org/10.1039/C4RA06044J