Asymmetric synthesis of (1R,2S,3R)-gamma-methyl-cis-pentacin by a kinetic resolution protocol

Bailey, SimonDavies, Stephen G.Smith, Andrew D.Withey, Jonathan M.2015-04-172022-05-272022-05-272002Bailey, S., Davies, S. G., Smith, A. D., & Withey, J. M. (2002). Asymmetric synthesis of (1R,2S,3R)-gamma-methyl-cis-pentacin by a kinetic resolution protocol. Chemical Communications, (23), 2910-2911. DOI: 10.1039/b209728chttps://hdl.handle.net/20.500.14078/278The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-amino-cyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-alpha-methylbenzylamide.34 kbenAll Rights Reservedasymmetric synthesiskinetic resolution protocolAsymmetric synthesis of (1R,2S,3R)-gamma-methyl-cis-pentacin by a kinetic resolution protocolAsymmetric synthesis of (1R,2S,3R)-gamma-methyl-cis-pentacin by a kinetic resolution protocolArticlehttps://doi.org/10.1039/b209728c