Narnaware, YuwarajKelly, ScottWoo, Norman2017-04-132022-05-282022-05-281997Narnaware, Y. K., Kelly, S. P. & Woo, N. Y. S. (1997). Effect of exogenous growth hormone on phagocytosis in Silver sea bream (Sparus sarba) adapted to hyper- and hypo-osmotic salinity. Fish and Shellfish Immunology, 7(7), 515-517. doi: 10.1006/fsim.1997.0103https://hdl.handle.net/20.500.14078/814Growth hormone (GH) is known to exert a myriad of functions throughout the vertebrates and in fish, its growth-stimulating and osmoregulatory e#ects are most prominent (Sakamoto et al., 1993; Chen et al., 1994). In mammals, GH is generally considered to be the principal hormone which exerts immunoregulatory properties and there is recent evidence for a similar e#ect of GH in fish (Sakai et al., 1996a,b,c). GH influences the immune processes from antibody formation to the appearance of di#erentiation markers on lymphocytes and augments the cytolytic activity of T cells, their proliferation and delayed type hyper-sensitivity (Blalock, 1989, 1994). These also include the enhancement of natural killer cell activity, mitogenic responses of lymphocytes and antibody production (Kelley, 1989).enAll Rights Reservedsea breamnon-specific immunitysalinitygrowth hormonemacrophage phagocytosisArticlehttps://doi.org/10.1006/fsim.1997.0103