Anton, Cristina2016-08-082022-05-282022-05-282016https://hdl.handle.net/20.500.14078/1059Presented on July 14 & 15, 2016 at the "International Biometric Conference" held at the Victoria Convention Centre in Victoria, B.C.We propose a model based on the logistic equation and linear kinetics to study the effect of toxicants with various initial concentrations on a cells' population. To efficiently estimate the model's parameters, we design an Expectation Maximization algorithm. The model is validated by showing that it accurately represents the information provided by in-vitro experiments.188 kbPDFenAll Rights Reservedtoxicologylinear kineticslogistic equationin-vitro experimentsParameter estimation and prediction for time-dependent concentration response curves for cytotoxicity assessmentPresentation