Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate

Davies, Stephen G.Díez, DavidEl Hammouni, Mohamed M.Garner, A. ChristopherGarrido, Narciso M.Long, Marcus J. C.Morrison, Rachel M.Smith, Andrew D.Sweet, Miles J.Withey, Jonathan M.2016-01-272022-05-272022-05-272003Davies, S. G., Díez, D., El Hammouni, M. M., Garner, A. C., Garrido, N. M., Long, M. C., & ... Withey, J. M. (2003). Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate. Chemical Communications, 19, 2410-2411. Retrieved from http://pubs.rsc.orghttps://hdl.handle.net/20.500.14078/469Comparison of the kinetic and parallel kinetic resolutions of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate allows for the efficient synthesis of both (1R,2S,5S)- and (1S,2R,5R)-enantiomers of methyl 2-amino-5-tert-butyl-cyclopentane-1-carboxylate.enAll Rights Reservedkinetic resolutionchemistryPreparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-tert-butyl-cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylateArticlehttps://doi.org/10.1039/b308855c