Poole, HaileyGauthier, JeremyVanderveen, Jesse R.Jessop, Philip G.Lee, Roland2021-06-142022-05-312022-05-312019Hailey Poole, Jeremy Gauthier, Jesse Vanderveen, Philip G. Jessop and Roland Lee. 2019. Use of a switchable-hydrophilicity solvent as both solvent and catalyst in aldol condensation. Green chemistry, 21 (23), pp. p6263-p6267 DOI: 10.1039/c9gc02593fhttps://hdl.handle.net/20.500.14078/2332A switchable-hydrophilicity solvent, N,N-dimethylcyclohexylamine, was used as a recyclable catalyst and solvent for aldol condensation, giving >97% pure product in 94% isolated yield without the need for purification or additional solvents. CO2-triggered separation produced yields greater than conventional workup and allowed facile recycling of the amine.enAll Rights Reservedswitchable-hydrophilicity solventN,N-dimethylcyclohexylaminealdol condensationwaste treatmentrecyclable catalystUse of a switchable-hydrophilicity solvent as both a solvent and a catalyst in aldol condensationArticle