Effect of injected growth hormone on phagocytosis in silver sea bream (Sparus sarba) adapted to hyper- and hypo-osmotic salinities

Narnaware, Yuwaraj
Kelly, Scott
Woo, Norman
Faculty Advisor
sea bream , non-specific immunity , salinity , growth hormone , macrophage phagocytosis
Abstract (summary)
Growth hormone (GH) is known to exert a myriad of functions throughout the vertebrates and in fish, its growth-stimulating and osmoregulatory e#ects are most prominent (Sakamoto et al., 1993; Chen et al., 1994). In mammals, GH is generally considered to be the principal hormone which exerts immunoregulatory properties and there is recent evidence for a similar e#ect of GH in fish (Sakai et al., 1996a,b,c). GH influences the immune processes from antibody formation to the appearance of di#erentiation markers on lymphocytes and augments the cytolytic activity of T cells, their proliferation and delayed type hyper-sensitivity (Blalock, 1989, 1994). These also include the enhancement of natural killer cell activity, mitogenic responses of lymphocytes and antibody production (Kelley, 1989).
Publication Information
Narnaware, Y. K., Kelly, S. P. & Woo, N. Y. S. (1997). Effect of exogenous growth hormone on phagocytosis in Silver sea bream (Sparus sarba) adapted to hyper- and hypo-osmotic salinity. Fish and Shellfish Immunology, 7(7), 515-517. doi: 10.1006/fsim.1997.0103
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