Effect of injected growth hormone on phagocytosis in silver sea bream (Sparus sarba) adapted to hyper- and hypo-osmotic salinities
sea bream, non-specific immunity, salinity, growth hormone, macrophage phagocytosis
Growth hormone (GH) is known to exert a myriad of functions throughout the vertebrates and in fish, its growth-stimulating and osmoregulatory e#ects are most prominent (Sakamoto et al., 1993; Chen et al., 1994). In mammals, GH is generally considered to be the principal hormone which exerts immunoregulatory properties and there is recent evidence for a similar e#ect of GH in fish (Sakai et al., 1996a,b,c). GH influences the immune processes from antibody formation to the appearance of di#erentiation markers on lymphocytes and augments the cytolytic activity of T cells, their proliferation and delayed type hyper-sensitivity (Blalock, 1989, 1994). These also include the enhancement of natural killer cell activity, mitogenic responses of lymphocytes and antibody production (Kelley, 1989).
Narnaware, Y. K., Kelly, S. P. & Woo, N. Y. S. (1997). Effect of exogenous growth hormone on phagocytosis in Silver sea bream (Sparus sarba) adapted to hyper- and hypo-osmotic salinity. Fish and Shellfish Immunology, 7(7), 515-517. doi: 10.1006/fsim.1997.0103
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