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Editorial: multiscale modeling for the liver

Faculty Advisor




liver, modeling, multiscale, transplantation, paracetamol (acetaminophen), hepatotoxicity, microstructure

Abstract (summary)

The liver is the central metabolic organ in the mammalian body. Hepatic functions need to be understood from a multiscale perspective, i.e., at the organism, organ, lobular, cellular, and molecular levels that can span vastly different timeframes, e.g., from milliseconds of molecular events to months or years of chronic disease formation (cf. Figure 1). Computational models coupled with experimental measurements and clinical observations provide a viable and cost-effective means to investigate hepatic function. The Research Topic collected some recent results, clinical observations, and updated reviews or perspectives; the seven contributions are briefed below.

Publication Information

Ho, H., Rezania, V., & Schwen, L. O. (2023). Editorial: Multiscale modeling for the liver. Frontiers in Bioengineering and Biotechnology, 11:1179980.


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Attribution (CC BY)