A pathogen imprinted hybrid polymer capacitive sensor for selective Escherichia coli detection

Author
Mugo, Samuel
Lu, Weihao
Dhanjai, Dhanjai
Faculty Advisor
Date
2020
Keywords
cell imprinted polymers , E. coli capacitive sensor , pathogen imprinted polymers
Abstract (summary)
A versatile pathogen imprinted polymer electrochemical sensor has been developed for Escherichia coli detection. The sensor is based on layer by layer assembly of multi-walled carbon nanotubes (CNT), nanocellulose (CNC) films, integrated with polyaniline (PANI) doped phenylboronic acid (PBA). The sensing layer is a poly(methacrylic acid) based pathogen microcontact imprinted polymer (PIP). The PIP@PBA/PANI@CNT/CNC sensor exhibits a high affinity towards E. coli in real biological matrices, while effective in discriminating E. coli amidst other bacteria. Using capacitance and impedance as transduction methods, the PIP sensor recorded a low limit of E. coli detection of 8.7 ± 0.5 cfu/ml, with a rapid response of ≤5 min.
Publication Information
Mugo, S. M., Lu, W., & Dhanjai, D. (2020). A pathogen imprinted hybrid polymer capacitive sensor for selective Escherichia coli detection. Medical devices and sensors, 3, Article e10071. https://doi.org/10.1002/mds3.10071
DOI
Notes
Item Type
Article
Language
English
Rights
All Rights Reserved