A pathogen imprinted hybrid polymer capacitive sensor for selective Escherichia coli detection

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dc.contributor.authorMugo, Samuel
dc.contributor.authorLu, Weihao
dc.contributor.authorDhanjai, Dhanjai
dc.date.accessioned2021-06-17
dc.date.accessioned2022-05-31T01:43:57Z
dc.date.available2022-05-31T01:43:57Z
dc.date.issued2020
dc.description.abstractA versatile pathogen imprinted polymer electrochemical sensor has been developed for Escherichia coli detection. The sensor is based on layer by layer assembly of multi-walled carbon nanotubes (CNT), nanocellulose (CNC) films, integrated with polyaniline (PANI) doped phenylboronic acid (PBA). The sensing layer is a poly(methacrylic acid) based pathogen microcontact imprinted polymer (PIP). The PIP@PBA/PANI@CNT/CNC sensor exhibits a high affinity towards E. coli in real biological matrices, while effective in discriminating E. coli amidst other bacteria. Using capacitance and impedance as transduction methods, the PIP sensor recorded a low limit of E. coli detection of 8.7 ± 0.5 cfu/ml, with a rapid response of ≤5 min.
dc.format.extent1.03MB
dc.format.mimetypePDF
dc.identifier.citationMugo, S. M., Lu, W., & Dhanjai, D. (2020). A pathogen imprinted hybrid polymer capacitive sensor for selective Escherichia coli detection. Medical devices and sensors, 3, Article e10071. https://doi.org/10.1002/mds3.10071
dc.identifier.doihttps://doi.org/10.1002/mds3.10071
dc.identifier.urihttps://hdl.handle.net/20.500.14078/2345
dc.languageEnglish
dc.language.isoen
dc.rightsAll Rights Reserved
dc.subjectcell imprinted polymers
dc.subjectE. coli capacitive sensor
dc.subjectpathogen imprinted polymers
dc.titleA pathogen imprinted hybrid polymer capacitive sensor for selective Escherichia coli detection
dc.typeArticle
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