The submerged plus maze as an assay for studying anxiety-like behaviour in fish

Author
Hope, Brittany V.
Hamilton, Trevor
Hurd, Peter L.
Faculty Advisor
Date
2019
Keywords
elevated plus maze , anxiety-testing , behavioural testing , fish behaviour , anxiolytic , anxiogenic
Abstract (summary)
The elevated plus maze is a commonly used and well-validated test of anxiety-related behaviour in rodents. The use of fish in behavioural neuroscience paradigms is increasing, necessitating an equivalent test for studying anxiety-like behaviour in fish. Because behaviour in the elevated plus maze is driven by aversion to open space, the submerged plus maze described here uses transparent walls to elicit similar behaviour in fish. The tendency of fish to explore or avoid the sections of the maze containing transparent walls is used as proxy for anxiety level. This submerged plus maze was designed and validated for convict cichlid (Amatitlania nigrofasciata) fish.
Publication Information
Hope, B., Hamilton, T.J., Hurd, P. (2019). The submerged plus maze as an assay for studying anxiety-like behaviour in fish. The submerged plus maze as an assay for studying anxiety-like behaviour in fish. MethodsX. 6:1832-1837. doi.org/10.1016/j.mex.2019.07.002
DOI
Notes
Item Type
Article
Language
English
Rights
Attribution (CC BY)