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The submerged plus maze as an assay for studying anxiety-like behaviour in fish

dc.contributor.authorHope, Brittany V.
dc.contributor.authorHamilton, Trevor
dc.contributor.authorHurd, Peter L.
dc.date.accessioned2020-07-29
dc.date.accessioned2022-05-31T01:15:07Z
dc.date.available2022-05-31T01:15:07Z
dc.date.issued2019
dc.description.abstractThe elevated plus maze is a commonly used and well-validated test of anxiety-related behaviour in rodents. The use of fish in behavioural neuroscience paradigms is increasing, necessitating an equivalent test for studying anxiety-like behaviour in fish. Because behaviour in the elevated plus maze is driven by aversion to open space, the submerged plus maze described here uses transparent walls to elicit similar behaviour in fish. The tendency of fish to explore or avoid the sections of the maze containing transparent walls is used as proxy for anxiety level. This submerged plus maze was designed and validated for convict cichlid (Amatitlania nigrofasciata) fish.
dc.format.extent610.45KB
dc.format.mimetypePDF
dc.identifier.citationHope, B., Hamilton, T.J., Hurd, P. (2019). The submerged plus maze as an assay for studying anxiety-like behaviour in fish. The submerged plus maze as an assay for studying anxiety-like behaviour in fish. MethodsX. 6:1832-1837. doi.org/10.1016/j.mex.2019.07.002
dc.identifier.doihttps://doi.org/10.1016/j.mex.2019.07.002
dc.identifier.urihttps://hdl.handle.net/20.500.14078/1659
dc.languageEnglish
dc.language.isoen
dc.rightsAttribution (CC BY)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectelevated plus maze
dc.subjectanxiety-testing
dc.subjectbehavioural testing
dc.subjectfish behaviour
dc.subjectanxiolytic
dc.subjectanxiogenic
dc.titleThe submerged plus maze as an assay for studying anxiety-like behaviour in fishen
dc.typeArticle

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