Determination of β-estradiol by surface-enhance raman spectroscopy (SERS) using a surface imprinted methacrylate polymer on nanoporous biogenic silica
dc.contributor.author | Mugo, Samuel | |
dc.contributor.author | Lu, Weihao | |
dc.date.accessioned | 2022-09-30 | |
dc.date.accessioned | 2022-10-12T21:20:38Z | |
dc.date.available | 2022-10-12T21:20:38Z | |
dc.date.issued | 2021 | |
dc.description.abstract | A phytoplankton derived nanoporous biogenic silica (BS) scaffold grafted with polymethacrylate β-estradiol molecularly imprinted polymers (MIP) film (MIP@BS) is reported as a selective platform for the determination of β-estradiol using surfaced-enhanced Raman scattering (SERS). The biogenic silica nanoparticles provided high surface area support for the MIP while serving as an active signal enhancement substrate for SERS. The MIP@BS platform demonstrated an excellent linear response (R2 = 0.9996) between 0.1 and 4 ng/mL of β-estradiol standards. The limit of detection (LOD) for the MIP@BS SERS sensor for β-estradiol was 0.073 ng/mL. The MIP@BS SERS sensors were successfully evaluated for the determination of β-estradiol in milk, while demonstrating good stability and reusability. | |
dc.description.uri | https://library.macewan.ca/cgi-bin/SFX/url.pl/CWF | |
dc.identifier.citation | S.M. Mugo, W. Lu. Determination of β-Estradiol by Surface-Enhance Raman Spectroscopy (SERS) Using a Surface Imprinted Methacrylate Polymer on Nanoporous Biogenic Silica. Analytical Letters, 2021. https://doi.org/10.1080/00032719.2021.1932969 | |
dc.identifier.doi | https://doi.org/10.1080/00032719.2021.1932969 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14078/2826 | |
dc.language | English | |
dc.language.iso | en | |
dc.rights | All Rights Reserved | |
dc.subject | β-estradiol | |
dc.subject | β-estradiol molecularly imprinted methacrylate polymers | |
dc.subject | nanoporous biogenic silica (BS) | |
dc.subject | surface enhanced Raman spectroscopy (SERS) | |
dc.subject | surface polymerization | |
dc.title | Determination of β-estradiol by surface-enhance raman spectroscopy (SERS) using a surface imprinted methacrylate polymer on nanoporous biogenic silica | en |
dc.type | Article |