Parameter estimation and prediction for time-dependent concentration response curves for cytotoxicity assessment

Simple item page
dc.contributor.authorAnton, Cristina
dc.date.accessioned2016-08-08
dc.date.accessioned2022-05-28T00:38:37Z
dc.date.available2022-05-28T00:38:37Z
dc.date.issued2016
dc.descriptionPresented on July 14 & 15, 2016 at the "International Biometric Conference" held at the Victoria Convention Centre in Victoria, B.C.
dc.description.abstractWe propose a model based on the logistic equation and linear kinetics to study the effect of toxicants with various initial concentrations on a cells' population. To efficiently estimate the model's parameters, we design an Expectation Maximization algorithm. The model is validated by showing that it accurately represents the information provided by in-vitro experiments.
dc.format.extent188 kb
dc.format.mimetypePDF
dc.identifier.urihttps://hdl.handle.net/20.500.14078/1059
dc.languageEnglish
dc.language.isoen
dc.rightsAll Rights Reserved
dc.subjecttoxicology
dc.subjectlinear kinetics
dc.subjectlogistic equation
dc.subjectin-vitro experiments
dc.titleParameter estimation and prediction for time-dependent concentration response curves for cytotoxicity assessment
dc.typePresentation
dspace.entity.type
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Parameter_estimation_and_prediction_for-_2016_roam.pdf
Size:
186.24 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Department of Mathematics and Statistics