Parameter estimation and prediction for time-dependent concentration response curves for cytotoxicity assessment

dc.contributor.author	Anton, Cristina
dc.date.accessioned	2016-08-08
dc.date.accessioned	2022-05-28T00:38:37Z
dc.date.available	2022-05-28T00:38:37Z
dc.date.issued	2016
dc.description	Presented on July 14 & 15, 2016 at the "International Biometric Conference" held at the Victoria Convention Centre in Victoria, B.C.
dc.description.abstract	We propose a model based on the logistic equation and linear kinetics to study the effect of toxicants with various initial concentrations on a cells' population. To efficiently estimate the model's parameters, we design an Expectation Maximization algorithm. The model is validated by showing that it accurately represents the information provided by in-vitro experiments.
dc.format.extent	188 kb
dc.format.mimetype	PDF
dc.identifier.uri	https://hdl.handle.net/20.500.14078/1059
dc.language	English
dc.language.iso	en
dc.rights	All Rights Reserved
dc.subject	toxicology
dc.subject	linear kinetics
dc.subject	logistic equation
dc.subject	in-vitro experiments
dc.title	Parameter estimation and prediction for time-dependent concentration response curves for cytotoxicity assessment	en
dc.type	Presentation
dspace.entity.type

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