Clustering of time series cytotoxicity data
concentration response curves, self organizing maps, toxicants
To study the effect of various toxicants on cells’ growth, the Alberta Centre for Toxicology did several in-vitro experiments, and concentration response curves (TCRCs) were generated. Each TCRC represents a time series that gives the temporal evolution of the number of cells, after exposure to a chemical with a certain concentration. Here we use the wavelet transform to extract important features from the original TCRC data, and we apply self organizing maps to classify the toxicants according to their adverse biological response.
Presented in absentia on April 27, 2020 at Student Research Day held at MacEwan University in Edmonton, Alberta. (Conference cancelled.) Also presented on June 19-22, 2019 at the Classification Society meeting held at MacEwan University in Edmonton, Alberta.
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