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Effects of food deprivation and refeeding on neuropeptide Y (NPY) mRNA levels in goldfish

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dc.contributor.authorNarnaware, Yuwaraj
dc.contributor.authorPeter, Richard E.
dc.date.accessioned2017-04-12
dc.date.accessioned2022-05-28T00:36:54Z
dc.date.available2022-05-28T00:36:54Z
dc.date.issued2001
dc.description.abstractIn mammals, NPY is a key factor in the regulation of feeding behavior. In the present study, the effects of refeeding for 1–3 h in 72–75-h food deprived (FD) goldfish on the levels of NPY mRNA in telencephalon-preoptic (TEL-POA), hypothalamus (HYP) and optic tectum-thalamus (OT-THAL) were examined, using Northern blot analysis. Goldfish FD for 72 h exhibited a significant increase in NPY mRNA levels in all brain regions. At 1 h after 72-h FD (73-h FD), NPY mRNA was significantly increased in TEL-POA and OT-THAL, but remained the same as 72-h FD fish in HYP. At 3 h after 72-h FD (75 h), all brain regions exhibited a significant increase in NPY mRNA levels. However, subsequent refeeding for 1–3 h rapidly and completely reversed the effects of FD in all brain regions, reaching fed levels within 1–3 h of refeeding. Serum GH levels were highest in 72-h FD fish, but decreased significantly over 1–3 h after 72-h FD; whereas, refeeding reversed the increase in serum GH levels only at 3 h after refeeding. Taken together, these results further support that NPY is a physiological brain transducer involved in the regulation of daily appetite and feeding in goldfish.
dc.description.urihttps://library.macewan.ca/cgi-bin/SFX/url.pl/93Y
dc.identifier.citationNarnaware, Y.K., & Peter, R.E. (2001a). Effect of food deprivation and refeeding on neuropeptide Y gene expression in goldfish. Comparative Biochemistry and Physiology, 129, 633-637. doi: 10.1016/S1096-4959(01)00359-1
dc.identifier.doihttps://doi.org/10.1016/S1096-4959(01)00359-1
dc.identifier.urihttps://hdl.handle.net/20.500.14078/808
dc.languageEnglish
dc.language.isoen
dc.rightsAll Rights Reserved
dc.subjectappetite
dc.subjectbrain
dc.subjectfood intake
dc.subjectfood deprivation
dc.subjectgrowth hormone
dc.subjectgene expression
dc.subjectgoldfish
dc.subjectneuropeptide Y
dc.subjectrefeeding
dc.subjectstarvation
dc.titleEffects of food deprivation and refeeding on neuropeptide Y (NPY) mRNA levels in goldfishen
dc.typeArticle
dspace.entity.type

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